La prima giornata del campionato inglese regala subito grosse sorprese: le “vespe” vanno a vincere in casa dei campioni in carica, Exeter corsara sul campo dei Tigers. Il derby di Londra va agli Harlequins, che battono 29-24 i London Irish
Saturday, 3 September 2011
| Leicester | 28 – 30 (15 – 23) |
Exeter | R |
| Tries: Waldrom, Morris 2 |
Tries: Naqelevuki, Johnson, Jess |
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| Penalties: Twelvetrees 2 |
Penalties: Mieres 3 |
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| Drop-goals: Ford |
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| Conversions: Twelvetrees 2 |
Conversions: Mieres 3 |
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| Welford Road | |||
| London Irish | 24 – 29 (6 – 13) |
Harlequins | R |
| Tries: Ojo 2 |
Tries: Johnston, Monye |
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| Penalties: Homer 4 |
Penalties: Evans 5 |
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| Conversions: Homer |
Conversions: Evans 2 |
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| Twickenham | |||
| Newcastle | 9 – 22 (9 – 13) |
Bath | L |
| Tries: Carraro |
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| Penalties: Gopperth 3 |
Penalties: Vesty 4 |
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| Drop-goals: Vesty |
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| Conversions: Vesty |
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| Kingston Park | |||
| Saracens | 15 – 20 (9 – 13) |
Wasps | R |
| Tries: Wade, Varndell |
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| Penalties: Farrell 2, Powell, Hodgson 2 |
Penalties: Robinson 2 |
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| Conversions: Robinson 2 |
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| Twickenham | |||
| Worcester | 17 – 12 (7 – 6) |
Sale | R |
| Tries: Benjamin |
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| Penalties: Goode |
Penalties: MacLeod 3 |
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| Drop-goals: MacLeod |
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| Conversions: Goode 2 |
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| Sixways Stadiu | |||
Il Grillotalpa 